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In a recent series of 70 patients with RCDI, FMT was effective even in patients with the C. A retrospective multicenter follow-up study of RCDI patients treated with FMT demonstrated a 91 primary cure rate and a 98 secondary cure rate (101).
The potential for transmission of infectious agents is a concern, however, and a recent publication outlines rigorous screening of stool donors blood and stool for common bacterial and viral enteropathogens (85). In one series, a standardized filtered, frozen, and then thawed preparation of stool from pre-screened universal donors showed cure rates equal to or better than those from patient-identified donors (103).